| | X Speed (06zy14vr) | Items | An item that boosts the Speed stat of a Pokémon during a battle. It wears off once the Pokémon is withdrawn. | RegionKanto |
| | Yache Berry (06tugehd) | Berries | If held by a Pokémon, this Berry will lessen the damage taken from one supereffective Ice-type attack. | RegionSinnoh |
| | Yellow Apricorn (06iok1k5) | Items | A yellow Apricorn. It has an invigorating scent. It can be made into a Moon Ball. | RegionJohto |
| | Yellow Flute (06a9eu6c) | Items | A yellow flute made from blown glass. Its melody snaps a single Pokémon out of confusion. It can be sold for a high price. | RegionHoenn |
✓ | | Yellow Nectar (0688i4so) | Items | A flower nectar obtained at Melemele Meadow. It changes the form of certain species of Pokémon. | RegionAlola |
| | Yellow Scarf (065yshdt) | Hold Items | An item to be held by a Pokémon. It boosts the Tough aspect of the holder in a Contest. | RegionHoenn |
| | Yellow Shard (06lrkb5g) | Items | A small yellow shard. It appears to be from some sort of implement made long ago. | RegionHoenn |
| | Zap Plate (069xfx17) | Hold Items | An item to be held by a Pokémon. It's a stone tablet that boosts the power of Electric-type moves. | RegionSinnoh |
| | Zigzag Scale (06i621lr) | Crafting | A small, zigzag shaped scale. It can be sold cheaply to shops, used for crafting or used in quests. | RegionHUB |
✓ | | Zinc (06vdfq2e) | Medicine | A nutritious drink for Pokémon. When consumed, it raises the Sp. Def EVs of a single Pokémon. | RegionHoenn |
| | Zoom Lens (062fdu3r) | Hold Items | An item to be held by a Pokémon. If the holder moves after its target moves, its accuracy will be boosted. | RegionSinnoh |